Current Projects

The Epidemiology of Obesity Metabolism in the Menopausal Transition

Much remains unknown regarding the mechanisms which underlie the cardio-vascular disease (CVD) risk associated with obesity, especially given that not all obese individuals possess the associated metabolic derangements that place them at greater CVD risk. A systematic examination of the effects of ovarian aging on obesity metabolism in relation to CVD risk markers is needed to better distinguish between those who will likely suffer obesity-associated cardiovascular complications and those who will not.

This study will characterize the development and longitudinal progression of CVD risk factors in relation to biochemical markers of obesity metabolism in a multi-ethnic population of women, considering the 10-year period of the menopausal transition. In the process, the study will provide unique and important information to address the public health obesity crisis at the age threshold for expression of chronic diseases of the elderly.

This study is conducted in partnership with Dr. Rachel Wildman   at the Albert Einstein School of Medicine  .